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Other Singal pathway


  • Vorapaxar EY2757

    Vorapaxar is a thrombin receptor (protease-activated receptor, PAR-1) antagonist.

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  • Riociguat EY2760

    Riociguat是可溶的鸟苷酸环化酶刺激剂。

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  • Molidustat EY2761

    Molidustat is a novel inhibitor of hypoxia-inducible factor (HIF) prolyl hydroxylase (PH) which stimulates erythropoietin (EPO) production and the formation of red blood cells.

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  • Pimavanserin EY2762

    Pimavanserin is a potent and selective serotonin 5-HT2A inverse agonist with pIC50 of 8.73, used to treat psychosis associated with Parkinson’s disease.

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  • Oclacitinib EY2763

    Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases.

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