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Other Singal pathway


  • GLPG0187 EY2848

    GLPG0187是广谱的integrin受体拮抗剂，具有抗肿瘤活性；抑制αvβ1-integrin的IC50值为1.3 nM。

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  • ASP8273 EY2847

    ASP8273 is a small molecule, irreversible TKI inhibitor that inhibits the kinase activity of EGFR mutations including T790M, with limited activity against EGFR wild-type NSCLC. In the in vitro enzymatic and cell-based assays, ASP8273 were evaluated against EGFR mutantsand WT EGFR.

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  • EGF-816 EY2846

    EGF816 is a third-generation covalent EGFR inhibitor that has potent inhibitory activity against activating and resistant T790M mutants with low IC50 in various cellular assays.

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  • HM-71224 EY2845

    HM-71224 is an EGFR tyrosine kinase inhibitor.

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  • Purpald EY2839

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