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EGFR


The epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is the cell-surface receptor for members of the epidermal growth factor family (EGF family) of extracellular protein ligands.
The epidermal growth factor receptor is a member of the ErbB family of receptors, a subfamily of four closely related receptor tyrosine kinases: EGFR (ErbB-1), HER2/c-neu (ErbB-2), Her 3 (ErbB-3) and Her 4 (ErbB-4). Mutations affecting EGFR expression or activity could result in cancer.

  • EGF-816 EY2846

    EGF816 is a third-generation covalent EGFR inhibitor that has potent inhibitory activity against activating and resistant T790M mutants with low IC50 in various cellular assays.

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  • HM-71224 EY2845

    HM-71224 is an EGFR tyrosine kinase inhibitor.

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  • Tyrphostin B44， (-) enantiomer EI2827

    Tyrphostin B44， (-) enantiomer是EGFR激酶的抑制剂。

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  • Tyrphostin B44， (+) enantiomer EI2828

    Tyrphostin B44， (+) enantiomer是EGFR激酶的抑制剂。

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  • PF 6274484 EI2135

    PF 6274484是高亲和性，活性的 covalent EGFR 激酶抑制剂。

    More

  • EGF-816 EY2846

    EGF816 is a third-generation covalent EGFR inhibitor that has potent inhibitory activity against activating and resistant T790M mutants with low IC50 in various cellular assays.

    More

  • HM-71224 EY2845

    HM-71224 is an EGFR tyrosine kinase inhibitor.

    More

  • Tyrphostin B44， (-) enantiomer EI2827

    Tyrphostin B44， (-) enantiomer是EGFR激酶的抑制剂。

    More

  • Tyrphostin B44， (+) enantiomer EI2828

    Tyrphostin B44， (+) enantiomer是EGFR激酶的抑制剂。

    More

  • PF 6274484 EI2135

    PF 6274484是高亲和性，活性的 covalent EGFR 激酶抑制剂。

    More

  • EGF-816 EY2846

    EGF816 is a third-generation covalent EGFR inhibitor that has potent inhibitory activity against activating and resistant T790M mutants with low IC50 in various cellular assays.

    More

  • HM-71224 EY2845

    HM-71224 is an EGFR tyrosine kinase inhibitor.

    More

  • Tyrphostin B44， (-) enantiomer EI2827

    Tyrphostin B44， (-) enantiomer是EGFR激酶的抑制剂。

    More

  • Tyrphostin B44， (+) enantiomer EI2828

    Tyrphostin B44， (+) enantiomer是EGFR激酶的抑制剂。

    More

  • PF 6274484 EI2135

    PF 6274484是高亲和性，活性的 covalent EGFR 激酶抑制剂。

    More
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