In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
BMS 195614是选择性 RARα 拮抗剂。
MoreBMS 191011是活性的 BKCa (KCa1.1) channel opener(通道开放剂)。
MoreBL 1249是Putative K2P2。1 (TREK-1) channel opener。
MoreBisindolylmaleimide II是活性的 PKC 抑制剂,nicotinic 受体拮抗剂。
MoreBiperiden hydrochloride是Muscarinic 受体拮抗剂, 对M1有一些选择活性。
More
