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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • BMS 753 EI0599

    BMS 753是RARα-选择性激动剂。

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  • BMS 493 EI0595

    BMS 493是Pan-RAR 反向激动剂。

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  • BMS 195614 EI0591

    BMS 195614是选择性 RARα 拮抗剂。

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  • BMS 191011 EI0589

    BMS 191011是活性的 BKCa (KCa1.1) channel opener（通道开放剂）。

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  • BL 1249 EI0587

    BL 1249是Putative K2P2。1 (TREK-1) channel opener。

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