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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    CGP 54626 hydrochloride是活性的， 选择性 GABAB 拮抗剂。

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  • CGP 53353 EI0754

    CGP 53353是PKCβII选择性抑制剂。

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  • CGP 52411 EI0753

    CGP 52411是EGFR 抑制剂。 也抑制 Aβ42 原纤成形。

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  • CGP 46381 EI0752

    CGP 46381是可透血脑屏障的， 选择性 GABAB 拮抗剂。

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  • CGP 39551 EI0750

    CGP 39551是活性选择性且竞争性的 NMDA 拮抗剂。

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