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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • CGP 39551 EI0750

    CGP 39551是活性选择性且竞争性的 NMDA 拮抗剂。

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  • CGP 36216 hydrochloride EI0747

    CGP 36216 hydrochloride是GABAB 拮抗剂， 对突触前受体展现活性。。

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  • CGP 35348 EI0746

    CGP 35348是选择性，可透血脑屏障的GABAB受体拮抗剂。

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  • CGP 13501 EI0743

    CGP 13501是GABAB 受体阳性调节剂。。

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  • CGH 2466 dihydrochloride EI0740

    CGH 2466 dihydrochloride是A1， A2B 和 A3 拮抗剂，p38 MAPK和PDE4的抑制剂。

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