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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Chetomin是阻断HIF-1α， HIF-2α 和 STAT2与CBP/p300的相互作用。

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  • CGS 20625 EI0769

    CGS 20625是Selective, partial agonist for the benzodiazepine binding site of the GABAA receptor。

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  • CGS 19755 EI0768

    CGS 19755是活性的， 竞争性NMDA 拮抗剂。

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  • CGP 7930 EI0762

    CGP 7930是GABAB 受体阳性调节剂。

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  • CGP 78608 hydrochloride EI0761

    CGP 78608 hydrochloride是活性的， 选择性甘氨酸位点的NMDA 拮抗剂。

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