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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    CID 2858522是选择性抑制 PKC诱导的 NF-κB 激活。

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  • CID 2745687 EI0792

    CID 2745687是GPR35 拮抗剂。

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  • CID 16020046 EI0791

    CID 16020046是选择性 GPR55 拮抗剂。

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  • CHPG EI0782

    CHPG是mGlu5 选择性激动剂。

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  • Chlormethiazole hydrochloride EI0778

    Chlormethiazole hydrochloride是增强 GABAA受体功能。

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