In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
CID 2858522是选择性抑制 PKC诱导的 NF-κB 激活。
MoreCID 2745687是GPR35 拮抗剂。
MoreCID 16020046是选择性 GPR55 拮抗剂。
MoreCHPG是mGlu5 选择性激动剂。
MoreChlormethiazole hydrochloride是增强 GABAA受体功能。
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