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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Co 101244 hydrochloride是高选择性 NR2B 拮抗剂。

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    CMPDA是GluR2 受体的阳性变构调节剂。

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    CMPD-1是非ATP竞争性 p38α 抑制剂， 也是微管蛋白聚合的抑制剂。

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    Clofibrate是PPAR 激动剂。

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