In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Conessine是活性选择性 H3 受体拮抗剂。
MoreCompound W是γ-secretase 抑制剂。
MoreCompound 401是选择性 DNA-PK,mTOR 抑制剂。
MoreCo 101244 hydrochloride是高选择性 NR2B 拮抗剂。
MoreCMPDA是GluR2 受体的阳性变构调节剂。
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