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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • CYM 5520 EI0907

    CYM 5520是选择性 S1P2 变构的激动剂(allosteric agonist)。

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  • CYM 5442 hydrochloride EI0906

    CYM 5442 hydrochloride是选择性S1P1受体激动剂。

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  • CYM 50308 EI0903

    CYM 50308是活性选择性 S1P4 激动剂。

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  • CYM 50260 EI0902

    CYM 50260是活性选择性 S1P4 激动剂。

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  • Cromakalim EI0880

    Cromakalim是Kir6 (KATP) 通道开放剂(channel opener)。

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