In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
DCG IV是高活性选择性 group II mGlu 激动剂。 也是NMDA 激动剂。
MoreDCB是mGlu5的变构的调节剂(allosteric modulator)。
MoreDC 260126是FFA1 (GPR40) 拮抗剂。
MoreDAU 5884 hydrochloride是M3 受体拮抗剂。
MoreD-Aspartic acid是NMDA 激动剂。
More