In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Dibutyryl-cAMP, sodium salt是细胞膜通透性 cAMP 类似物。
MoreDH 97是MT2 受体拮抗剂。
MoreDG 172 dihydrochloride是活性的 PPARβ/δ 反向激动剂,促进 BMC的分化。
MoreDFB是mGlu5变构的增强剂(allosteric potentiator)。
MoreDextromethorphan hydrobromide是NMDA 受体拮抗剂。
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