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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    DNQX是选择性 non-NMDA 拮抗剂。

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  • DMPQ dihydrochloride EI1013

    DMPQ dihydrochloride是PDGFRβ活性选择性抑制剂。

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  • DMNB EI1010

    DMNB是DNA-PK 抑制剂。

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  • DMeOB EI1008

    DMeOB是 mGlu5的阴性变构调节剂（negative allosteric modulator）。

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  • DL-AP7 EI1003

    DL-AP7是特异性NMDA 拮抗剂。

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