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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • DMeOB EI1008

    DMeOB是 mGlu5的阴性变构调节剂（negative allosteric modulator）。

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  • DL-AP7 EI1003

    DL-AP7是特异性NMDA 拮抗剂。

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  • DL-AP5 EI1001

    DL-AP5是活性选择性 NMDA 拮抗剂。

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  • DL-AP3 EI0998

    DL-AP3是Group I mGlu 拮抗剂。

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  • Diprenorphine EI0997

    Diprenorphine是非选择性 opioid 拮抗剂。

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