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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • DR 2313 EI1037

    DR 2313是PARP-1,PARP-2 抑制剂。

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  • DQP 1105 EI1036

    DQP 1105是选择性 NR2C/NR2D 受体拮抗剂。

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  • DPPI 1c hydrochloride EI1035

    DPPI 1c hydrochloride是Dipeptidyl peptidase IV (DPP-IV) 抑制剂。

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  • DPPE fumarate EI1034

    DPPE fumarate是细胞内结合部位的组胺结合抑制剂(blocker of histamine binding at the intracellular binding site)。

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  • DPO-1 EI1033

    DPO-1是KV1.5 通道和 IKur 电流的阻断剂(KV1.5 channel and IKur current )。

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