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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Grifolic acid EI1231

    Grifolic acid是选择性 部分 FFA4 (GPR120) 激动剂。

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  • GS 39783 EI1235

    GS 39783是GABAB 受体阳性调节剂（positive modulator）。

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  • GSK 137647 EI1238

    GSK 137647是活性选择性 FFA4 (GPR120) 激动剂。

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  • GSK 269962 EI1243

    GSK 269962是活性选择性 ROCK 抑制剂。

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  • GR 135531 EI1218

    GR 135531是高亲和性 melatonin MT3 配体。

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