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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    EGLU是高选择性 group II mGlu 拮抗剂。

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  • Edelfosine EI1058

    Edelfosine是选择性 PI-PLC 抑制剂， 也是PAF受体激动剂。

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  • Edaglitazone EI1057

    Edaglitazone是活性的，选择性 PPARγ 激动剂，抗糖尿病作用。

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  • EC 144 EI1053

    EC 144是高亲和性，活性的选择性 Hsp90 抑制剂。

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  • EB 47 EI1050

    EB 47是活性的 PARP-1 抑制剂。

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