Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • ADL5859 HCl EY0445

    ADL5859是δ-阿片受体选择性激动剂，Ki为0.8 nM，对hERG有弱抑制性。

    More

  • Anacardic Acid EY0450

    Anacardic Acid是一个有效的p300 and p300/CBP-associated factor histone acetyltranferases的抑制剂，也具有抗细菌和抗微生物活性，抑制前列腺素合成，并抑制酪氨酸酶和脂肪氧合酶。

    More

  • Fluocinolone Acetonide EY0434

    Fluocinolone Acetonide是糖皮质激素衍生物，可作用于各种皮肤病。

    More

  • Clofazimine EY0437

    Clofazimine是一种脂溶性亚氨基酚嗪类染料, 具有显著的抗炎效果, 与其它抗分支杆菌药物联用来AIDS和克罗恩病。

    More

  • GSK429286A EY0443

    GSK429286A是ROCK1和ROCK2的选择性抑制剂，IC50分别为14 nM和63 nM。

    More
    • Current page351, Total Pages360, Total Record1798 First Prev 349350351352353 Next Last Goto
More