Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Onalespib EY0339

    AT13387是一种有效的，选择性Hsp90抑制剂，作用于A375细胞，IC50为18 nM，具有较长时间的抗肿瘤活性。

    More

  • MK-0752 EY0340

    MK-0752是一种适度有效的γ-secretase（γ-分泌酶）抑制剂，降低Aβ40产量，IC50为5 nM。

    More

  • Tipifarnib EY0326

    Tipifarnib是特异的法尼基转移酶抑制剂，IC50为0.6 nM。

    More

  • Nelfinavir Mesylate EY0327

    Nelfinavir Mesylate 是口服的人HIV-1蛋白酶抑制剂，Ki为2nM。

    More

  • Ciclopirox ethanolamine EY0329

    Ciclopirox olamine是一种合成的抗真菌剂,用于浅部真菌病的局部皮肤病治疗, 针对花斑癣最有效。

    More
    • Current page349, Total Pages352, Total Record1759 First Prev 347348349350351 Next Last Goto
More