Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • JNJ-7777120 EY0895

    JNJ-7777120是一种选择性的组胺H4受体拮抗剂, Ki值为4 ±1 nM,比作用于其他组胺受体选择性高1000多倍。

    More

  • Ketoconazole EY0899

    Ketoconazole (酮康唑)是咪唑类抗真菌剂，是经典的CYP3A4抑制剂。

    More

  • MC1568 EY0886

    MC1568是 class II (IIa)HDAC选择性抑制剂，对HDAC II的IC50值220nM，对class I HDAC活性弱176倍。

    More

  • PD318088 EY0891

    PD318088是ATP非竞争性MEK1/2变构抑制剂，能与ATP同时结合于MEK1，且其结合位点与ATP结合位点相邻。

    More

  • Tenofovir Disoproxil Fumarate EY0893

    Tenofovir Disoproxil FumarateDisoproxil Fumarate能阻断HIV-1和HBV的逆转录酶，对HIV-1和HIV-2的IC50分别为0.5-2.2 uM和1.6-4.9 uM。

    More
    • Current page328, Total Pages352, Total Record1759 First Prev 326327328329330 Next Last Goto
More