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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Ac-Tyr-Val-Ala-Asp-CMK is a cell-permeable and irreversible inhibitor of caspase-1 (Ki = 760 pM), caspase-4, and caspase-5.

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    A cell-permeable inhibitor of caspase-1, caspase-4, and caspase-5.

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  • E-4031 EY2003

    E-4031阻断ATP敏感性钾通道，是抗心律失常剂。

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    Skepinone-L是一种选择性p38 MAPK抑制剂，IC50为5 nM。

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  • Chrysophanic Acid EY1844

    Chrysophanic acid, also known as chrysophanol, is a fungal isolate and a natural anthraquinone with anti-cancer activity.

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