Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • RG2833 EY1030

    RG2833(RGFP109)是可通过血脑屏障的HDAC抑制剂，对HDAC1和HDAC3的IC50分别为60nM和50nM。

    More

  • Pomalidomide EY1041

    Pomalidomide能抑制LPS诱导的TNF-α释放，IC50为13 nM。

    More

  • PD0325901 EY1046

    PD0325901是一种选择性的，ATP非竞争性的MEK抑制剂，IC50为0.33 nM，对ERK1和ERK2磷酸化抑制作用比CI-1040强500倍左右。

    More

  • Sodium Monensin EY0996

    Sodium Monensin从 Streptomyces cinnamonensis中分离的, 是一种众所周知的天然的聚醚 类离子载体抗生素的代表。

    More

  • Pioglitazone EY0997

    Pioglitazone是一种选择性过氧化物酶体增殖物激活受体γ激动剂。

    More
    • Current page258, Total Pages352, Total Record1759 First Prev 256257258259260 Next Last Goto
More