Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • R428 Bemcentinib EY1287

    R428是Axl抑制剂，IC50为14 nM。

    More

  • LMK-235 EY1289

    LMK235 是HDAC 抑制剂，对HDAC4 和 HDAC5具有特异性抑制作用，IC50值为 0.49 μM (A2780)、 0.32 μM (A2780 CisR)。

    More

  • FK866 EY1248

    FK866 (APO866, Daporinad)是一种有效的NAD抑制剂，因此可以抑制NAD依赖的烟酰胺转磷酸核糖基酶(NAMPT)的活性，IC50为0.09 nM。

    More

  • Pepstatin A EY1262

    Pepstatin是一种强效的天冬氨酸蛋白酶抑制剂。

    More

  • Ubenimex EY1237

    Ubenimex (Bestatin)是一种竞争性氨肽酶B抑制剂，作用于K562细胞，IC50为100 mg/ml。

    More
    • Current page257, Total Pages360, Total Record1798 First Prev 255256257258259 Next Last Goto
More