Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • AZD7762 EY1398

    AZD7762是Chk1的抑制剂，IC50为5 nM，对Chk2的抑制性与Chk1相近，但对CAM，Yes，Fyn，Lyn，Hck和Lck的抑制性较弱。

    More

  • H 89 2HCl EY1400

    H 89 2HCl是一种有效的PKA抑制剂，Ki为48 nM，作用于PKA比作用于PKG选择性高10倍，比作用于PKC， MLCK，钙调蛋白激酶II和酪蛋白激I/II选择性高500倍。

    More

  • Minocycline hydrochloride EY1402

    Minocycline HCl是一种脂溶性的活性最强的四环素类抗生素，结合到30S核糖体亚基，抑制tRNA与核糖体mRNA复合物结合，干扰蛋白质合成。

    More

  • NU7026 EY1404

    NU7026是一种有效的DNA-PK抑制剂，IC50为0.23 μM，作用于DNA-PK比作用于PI3K选择性高60倍，抑制ATM和ATR活性。

    More

  • Pioglitazone HCl EY1405

    Pioglitazone hydrochloride (盐酸吡格列酮; U 72107A; AD 4833) 是PPARγ刺激剂。

    More
    • Current page253, Total Pages360, Total Record1796 First Prev 251252253254255 Next Last Goto
More