Home > 暂无记录 暂无记录 Signal Pathway

Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Chloroquine Phosphate EY1843

    Chloroquine Phosphate是一种4-氨基喹啉的抗疟疾和抗风湿抑制剂。

    More

  • Lonafarnib EY1846

    Lonafarnib(Sch66336)是口服生物相容性的FPTase抑制剂，对H-ras，K-ras-4B和N-ras的IC50分别为1.9 nM，5.2 nM和2.8 nM。

    More

  • EHop-016 EY1818

    EHop-016是Rac GTPase高效选择性抑制剂，在MDA-MB-435细胞中IC50值1.1uM。

    More

  • Veliparib EY1819

    Veliparib (ABT-888)是一种有效的PARP1和PARP2抑制剂，Ki分别为5.2 nM和2.9 nM，抑制SIRT2。

    More

  • GSK126 EY1820

    GSK126是一种高活性，S-腺苷-蛋氨酸竞争性EZH2甲基转移酶抑制剂，Ki为0.5 nM。

    More
    • Current page230, Total Pages352, Total Record1759 First Prev 228229230231232 Next Last Goto
More