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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • L-364，373 EI1473

    L-364，373是KV7.1 离子通道激动剂激活IKs。

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  • L 006235 EI1463

    L 006235是活性的 cathepsin K 抑制剂。

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  • KG 5 EI1438

    KG 5是PDGFRβ， B-Raf， c-Raf， FLT3，KIT 的抑制剂。

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  • KN 92 EI1450

    KN 92是K+ channel (Kv)阻断剂。KN 93非活性的类似物。 。

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  • KN 93 EI1451

    KN 93是CaM 激酶 II 抑制剂， 也是K+ 通道阻断剂 (KV)。

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