In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Ipratropium bromide是Muscarinic 拮抗剂。
MoreIQ 3是选择性 JNK3 抑制剂。
MoreImpentamine dihydrobromide是选择性 H3 拮抗剂。
MoreIfenprodil hemitartrate是非竞争性 NMDA 拮抗剂。 也是 σ 的配体。
MoreImetit dihydrobromide是标准H3和H4 激动剂 (H3 > H4)。
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