In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Irsogladine maleate是PDE4 抑制剂, 抗溃疡试剂。
MoreIsoguvacine hydrochloride是选择性GABAA激动剂。
Moreiso-PPADS tetrasodium salt是P2X 拮抗剂。
MoreIodophenpropit dihydrobromide是活性选择性H3拮抗剂。
MoreIPAG是活性的 σ 拮抗剂。
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