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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    JTE 013是S1P2 受体拮抗剂。

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  • JNJ 47965567 EI1399

    JNJ 47965567是活性的，选择性 P2X7 拮抗剂， 可透血脑屏障。

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  • JNJ 5207852 dihydrochloride EI1401

    JNJ 5207852 dihydrochloride是高亲和性 H3 受体拮抗剂。

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  • JLK 6 EI1387

    JLK 6是γ-secretase-mediated βAPP processing抑制剂。

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  • JNJ 10181457 dihydrochloride EI1390

    JNJ 10181457 dihydrochloride是H3 拮抗剂。

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