In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
KG 5是PDGFRβ, B-Raf, c-Raf, FLT3,KIT 的抑制剂。
MoreKN 92是K+ channel (Kv)阻断剂。KN 93非活性的类似物。 。
MoreKN 93是CaM 激酶 II 抑制剂, 也是K+ 通道阻断剂 (KV)。
MoreKetamine hydrochloride是非竞争性 NMDA 受体拮抗剂。
MoreKetotifen fumarate是H1 拮抗剂。
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