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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • L-CCG-lll EI1519

    L-CCG-lll是活性的, 竞争性 glutamate uptake inhibitor(摄取抑制剂)。

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  • L-Cysteinesulfinic acid EI1520

    L-Cysteinesulfinic acid是NMDA,mGlu 激动剂。

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  • L-AP4 EI1505

    L-AP4是选择性 group III mGlu 激动剂。

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  • L-AP5 EI1506

    L-AP5是活性的, 选择性 NMDA 拮抗剂。  DL-AP5低活性形态。

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  • L-Aspartic acid EI1509

    L-Aspartic acid是NMDA 激动剂。

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