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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Methimepip dihydrobromide是极度高效的选择性 H3 激动剂。

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    Mephenytoin是CYP2C19 底物。 抗惊厥剂。

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    MDL 28170是活性选择性 calpain，cathepsin B 抑制剂。

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    MDL 12330A hydrochloride是Adenylyl cyclase 抑制剂， 也是cyclic nucleotide PDE 抑制剂。

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    Macbecin I是Hsp90 抑制剂。

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