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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    LOE 908 hydrochloride是广谱性的离子通道阻断剂, 神经保护活性。

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    Loreclezole hydrochloride是亚型选择性GABAA受体调节剂。

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    LG 101506是选择性 RXR 调节剂。

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    L-Glutamic acid是内源性非选择性激动剂。

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    Linopirdine dihydrochloride是KV7 (KCNQ) 通道阻断剂。

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