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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • ML 190 EI1709

    ML 190是选择性 κ opioid 受体拮抗剂。

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  • ML 193 EI1710

    ML 193是活性选择性 GPR55 拮抗剂。

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  • ML 213 EI1712

    ML 213是KV7.2，KV7.4 离子通道开启剂（channel opener）。

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  • MK 571 EI1697

    MK 571是活性的 CysLT1 (LTD4) 反向激动剂。 也是MRP1 抑制剂。

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  • ML 145 EI1703

    ML 145是GPR35 拮抗剂。

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