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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • ML 365 EI1727

    ML 365是活性的，选择性 TASK-1 通道阻断剂。

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  • ML 289 EI1718

    ML 289是选择性mGlu3阴性变构的调节剂（negative allosteric modulator）。

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  • ML 297 EI1719

    ML 297是选择性 Kir3.1/3.2 (GIRK1/2) 离子通道激动剂。

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  • ML 190 EI1709

    ML 190是选择性 κ opioid 受体拮抗剂。

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  • ML 193 EI1710

    ML 193是活性选择性 GPR55 拮抗剂。

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