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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    LY 255283是选择性竞争性BLT2受体拮抗剂。

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    Luzindole是竞争性 melatonin MT1/MT2 拮抗剂。

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  • LY 2183240 EI1584

    LY 2183240是新型活性的 anandamide uptake inhibitor（摄取抑制剂）， 抑制 FAAH。

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    L-Quisqualic acid是AMPA/group I mGlu 激动剂。

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  • LSN 2463359 EI1575

    LSN 2463359是活性的，选择性mGlu5阳性变构的调节剂（positive allosteric modulator）。

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