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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • MNI 137 EI1744

    MNI 137是选择性group II mGlu 受体阴性变构的调节剂（negative allosteric modulator）。

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  • MNI键和的D-aspartate EI1746

    MNI键和的D-aspartate是Caged D-aspartate， NMDA 激动剂。

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  • MM 11253 EI1736

    MM 11253是RARγ-选择性拮抗剂。

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  • ML 337 EI1721

    ML 337是选择性mGlu3阴性变构的调节剂（negative allosteric modulator）。

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  • ML 3403 EI1722

    ML 3403是p38 抑制剂。

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