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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • LY 367385 EI1605

    LY 367385是选择性 mGlu1a 拮抗剂。

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  • LY 379268 EI1606

    LY 379268是高选择性 group II mGlu 激动剂。

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  • LY 233053 EI1587

    LY 233053是竞争性 NMDA 受体拮抗剂。

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  • LY 235959 EI1588

    LY 235959是竞争性 NMDA 拮抗剂。

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  • LY 2389575 hydrochloride EI1590

    LY 2389575 hydrochloride是选择性mGlu3阴性变构调节剂（positive allosteric modulator）。

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