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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • LY 456236 hydrochloride EI1610

    LY 456236 hydrochloride是选择性 mGlu1 拮抗剂。

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  • LY 487379 hydrochloride EI1611

    LY 487379 hydrochloride是选择性mGlu2的阳性变构的调节剂（positive allosteric modulator）。

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  • LY 333531 hydrochloride EI1599

    LY 333531 hydrochloride是Protein kinase C 抑制剂，  β isozymes选择性。

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  • LY 341495 EI1601

    LY 341495是高活性的选择性 group II 拮抗剂。

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  • LY 354740 EI1604

    LY 354740是活性高选择性 group II mGlu 激动剂。

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