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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • MDL 28170 EI1640

    MDL 28170是活性选择性 calpain，cathepsin B 抑制剂。

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  • MDL 12330A hydrochloride EI1639

    MDL 12330A hydrochloride是Adenylyl cyclase 抑制剂， 也是cyclic nucleotide PDE 抑制剂。

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  • Macbecin I EI1625

    Macbecin I是Hsp90 抑制剂。

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  • MaxiPost EI1629

    MaxiPost是MaxiPost是K离子通道调节剂（MaxiPost exerts subtype-specific effects）。

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  • McN-A 343 EI1633

    McN-A 343是选择性 M1 muscarinic 激动剂。

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