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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • MTEP hydrochloride EI1794

    MTEP hydrochloride是活性选择性 mGlu5 拮抗剂。

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  • Muscimol EI1796

    Muscimol是活性的 GABAA 激动剂。

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  • MY-5445 EI1797

    MY-5445是PDE5 抑制剂。

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  • N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide EI1801

    N-[2-(Piperidinylamino)ethyl]-4-iodobenzamide是σ1 选择性配体。

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  • N1，N11-Diethylnorspermine tetrahydrochloride EI1802

    N1，N11-Diethylnorspermine tetrahydrochloride是Spermine，spermidine acetyltransferase的激活剂。

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