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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    ML 145是GPR35 拮抗剂。

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    MitMAB是Dynamin的抑制剂。

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    MK 0343是亚型选择性 GABAA 受体部分激动剂。

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    Miglustat hydrochloride是α-glucosidase I,II 抑制剂。 也抑制 ceramide-specific glycosyltransferases。

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