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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • MRK 016 EI1765

    MRK 016是α5选择性的GABAA反向激动剂。

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  • MRK 560 EI1766

    MRK 560是γ分泌酶（secretase） 抑制剂可以抑制淀粉样斑块沉积（amyloid plaque deposits）。

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  • MNI键和的L-glutamate EI1747

    MNI键和的L-glutamate是L-glutamate stable photoreleaser 。

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  • MNI键和的NMDA EI1748

    MNI键和的NMDA是Caged NMDA。

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  • Monastrol EI1753

    Monastrol是Mitotic kinesin Eg5 选择性抑制剂。

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