In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
MRS 2365是高活性选择性 P2Y1 激动剂。
MoreMRS 2500 tetraammonium salt是极高活性的,选择性 P2Y1 拮抗剂。
MoreMRS 2690是活性的 P2Y14 激动剂。
MoreMRS 2693 trisodium salt是选择性 P2Y6 激动剂。
MoreMRS 2768 tetrasodium salt是选择性 P2Y2 激动剂。
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