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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • NPS 2390 EI1934

    NPS 2390是Group I mGlu 拮抗剂。

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  • NQTrp EI1937

    NQTrp是Aβ 低聚物(oligomer)活性抑制剂，能抑制原纤维形成（fibril formation）。

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  • nor-Binaltorphimine dihydrochloride EI1917

    nor-Binaltorphimine dihydrochloride是经典的 κ 选择性 拮抗剂。

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  • Norketamine hydrochloride EI1918

    Norketamine hydrochloride是活性的， 非竞争性 NMDA 拮抗剂。

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  • NNC 711 EI1905

    NNC 711是GAT-1选择性抑制剂。

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