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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • NS 6180 EI1947

    NS 6180是活性的 KCa3.1 通道阻断剂。

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  • NS 8593 hydrochloride EI1948

    NS 8593 hydrochloride是选择性 KCa2 (SK) 通道的阴性调节剂（negative modulator）， 抑制 SK 电流。

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  • NSC 109555 ditosylate EI1950

    NSC 109555 ditosylate是选择性 Chk2 抑制剂。

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  • NSC 33994 EI1952

    NSC 33994是JAK2 抑制剂。

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  • NSC 3852 EI1953

    NSC 3852是组蛋白脱乙酰酶抑制剂HDAC（histone deacetylase）。

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