In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
NSC 624206是Ubiquitin-activating enzyme (E1) 抑制剂。
MoreNSC 693868是Cdk 抑制剂。 也抑制 GSK-3。
MoreNS 5806是KV4.3 channel 激动剂。
MoreNS 6180是活性的 KCa3.1 通道阻断剂。
MoreNS 8593 hydrochloride是选择性 KCa2 (SK) 通道的阴性调节剂(negative modulator), 抑制 SK 电流。
More
