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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Naloxonazine dihydrochloride是选择性 μ1 拮抗剂。

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  • Naloxone benzoylhydrazone EI1824

    Naloxone benzoylhydrazone是全 κ 激动剂， 部分 μ 和 δ 激动剂，可以拮抗激动剂诱导的NOP激活。。

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  • Naltriben mesylate EI1825

    Naltriben mesylate是经典 δ2 选择性拮抗剂。

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  • Naltrindole hydrochloride EI1826

    Naltrindole hydrochloride是选择性 非肽类 δ 拮抗剂。

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  • N20C hydrochloride EI1804

    N20C hydrochloride是非竞争性 NMDA 受体通道开启阻断剂（open-channel blocker.）。

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