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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Ocinaplon EI1988

    Ocinaplon是GABAA 调节剂，抗焦虑剂。

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  • NVP DPP 728 dihydrochloride EI1974

    NVP DPP 728 dihydrochloride是活性的，口服有效 dipeptidyl peptidase IV (DPP-IV) 抑制剂。

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  • O-1602 EI1978

    O-1602是活性的 GPR55 受体激动剂。

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  • nTZDpa EI1967

    nTZDpa是活性的， 选择性 PPARγ 部分激动剂。

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  • NU 1025 EI1968

    NU 1025是活性的 PARP 抑制剂。

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