In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Olopatadine hydrochloride是H1 拮抗剂, 眼部抗过敏剂。
MoreOctMAB是Dynamin 抑制剂。
MoreOcinaplon是GABAA 调节剂,抗焦虑剂。
MoreNVP DPP 728 dihydrochloride是活性的,口服有效 dipeptidyl peptidase IV (DPP-IV) 抑制剂。
MoreO-1602是活性的 GPR55 受体激动剂。
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