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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    NF 449是高选择性 P2X1 拮抗剂。

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  • NF 546 EI1878

    NF 546是选择性 P2Y11 激动剂。

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  • NG 25 EI1883

    NG 25是TGF-β-activated kinase (TAK1) 抑制剂。

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  • Nepicastat hydrochloride EI1853

    Nepicastat hydrochloride是活性的，选择性 dopamine β-hydroxylase (DBH) 抑制剂， 口服有效。

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  • NE 100 hydrochloride EI1848

    NE 100 hydrochloride是选择性 σ1 拮抗剂。

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