In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
NNC 711是GAT-1选择性抑制剂。
MoreNoladin ether是CB1 和 GPR55的内源性激动剂。
MoreN-MPPP Hydrochloride是选择性 κ 激动剂。
MoreNNC 05-2090 hydrochloride是GABA uptake inhibitor(摄取抑制剂),具有适当的 BGT-1 选择性。
MoreNNC 26-9100是选择性 sst4 激动剂。
More