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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    Norketamine hydrochloride是活性的， 非竞争性 NMDA 拮抗剂。

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  • NNC 711 EI1905

    NNC 711是GAT-1选择性抑制剂。

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    Noladin ether是CB1 和 GPR55的内源性激动剂。

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    N-MPPP Hydrochloride是选择性 κ 激动剂。

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    NNC 05-2090 hydrochloride是GABA uptake inhibitor（摄取抑制剂)，具有适当的 BGT-1 选择性。

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