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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • PD 166285 dihydrochloride EI2078

    PD 166285 dihydrochloride是活性的 Src 抑制剂， 也能抑制 FGFR1， PDGFRβ 和 Wee1。

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  • PD 166793 EI2079

    PD 166793是广谱的 MMP 抑制剂。

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  • PD 102807 EI2068

    PD 102807是选择性 M4 拮抗剂。

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  • PD 118057 EI2069

    PD 118057是选择性 KV11.1 (hERG) 通道激动剂。

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  • PD 144418 oxalate EI2071

    PD 144418 oxalate是高亲和性， 选择性 σ1 配体。

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