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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • PD 334581 EI2086

    PD 334581是MEK1 抑制剂。

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  • PD 407824 EI2088

    PD 407824是Chk1，Wee1选择性抑制剂。

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  • PDP-EA EI2091

    PDP-EA是FAAH 激动剂。

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  • PD 198306 EI2085

    PD 198306是MEK1/2的选择性抑制剂。

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  • PD 161570 EI2077

    PD 161570是选择性 FGFR 抑制剂。

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