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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • PF 06465469 EI2123

    PF 06465469是活性的 ITK 抑制剂， 也是抑制 BTK。

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  • PF 3845 EI2127

    PF 3845是选择性 FAAH 抑制剂。

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  • PETCM EI2115

    PETCM是Caspase-3的激动剂。

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  • PF 04418948 EI2116

    PF 04418948是活性选择性 EP2 受体拮抗剂。

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  • Penitrem A EI2095

    Penitrem A是活性选择性 BKCa (KCa1.1) 通道阻断剂。

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