In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
Oxycodone hydrochloride是μ 激动剂。
MoreP1075是活性的 Kir6 (KATP) 通道开启剂(channel opener)。
MoreP7C3是NAMPT 激动剂, 也具有亲神经性,神经保护活性(proneurogenic,neuroprotective)。
MoreOxotremorine M是毒蕈碱受体激动剂(muscarinic)。
MoreOxotremorine sesquifumarate是毒蕈碱受体激动剂(muscarinic)。
More
