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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • PHP 501 trifluoroacetate EI2167

    PHP 501 trifluoroacetate是活性的 GABAA 拮抗剂。

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  • Piclamilast EI2172

    Piclamilast是活性选择性 PDE4 抑制剂。

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  • Picrotoxin EI2173

    Picrotoxin是GABAA 受体拮抗剂。

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  • Phenobarbital sodium salt EI2156

    Phenobarbital sodium salt是加强 GABA能活性（GABAergic activity）。。

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  • PHCCC EI2153

    PHCCC是活性的 group I mGlu 拮抗剂。

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