In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.
PK-THPP是活性的 TASK-3 通道阻断剂。
MorePMPA (NMDA antagonist)是竞争性 NMDA 拮抗剂。
MorePIM-1 inhibitor 2是Pim-1 激酶抑制剂。
MorePirenzepine dihydrochloride是选择性 M1 muscarinic 受体拮抗剂。
MorePirlindole mesylate是MAO-A 抑制剂。
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