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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

  • Prostratin EI2243

    Prostratin是PKC的激动剂， 也是NF-κB的激动剂。

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  • Primidone EI2231

    Primidone是活性的iates GABAA 受体 function。

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  • Pregnanolone EI2227

    Pregnanolone是GABAA 受体阳性变构的调节剂（positive allosteric modulator。

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  • Pregnenolone sulfate sodium salt EI2228

    Pregnenolone sulfate sodium salt是NMDA 增效剂（potentiator）。

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  • PPDA EI2218

    PPDA是亚型选择性 NR2C/NR2D 拮抗剂。

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