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Signal Pathway


In some cases, receptor activation caused by ligand binding to a receptor is directly coupled to the cell's response to the ligand. For example, the neurotransmitter GABA can activate a cell surface receptor that is part of an ion channel. GABA binding to a GABAA receptor on a neuron opens a chloride-selective ion channel that is part of the receptor. GABAA receptor activation allows negatively charged chloride ions to move into the neuron, which inhibits the ability of the neuron to produce action potentials.

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    PD 198306是MEK1/2的选择性抑制剂。

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  • PD 161570 EI2077

    PD 161570是选择性 FGFR 抑制剂。

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  • PD 166285 dihydrochloride EI2078

    PD 166285 dihydrochloride是活性的 Src 抑制剂， 也能抑制 FGFR1， PDGFRβ 和 Wee1。

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  • PD 166793 EI2079

    PD 166793是广谱的 MMP 抑制剂。

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  • PD 102807 EI2068

    PD 102807是选择性 M4 拮抗剂。

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